NOVELTY - Method of preparing skipjack tuna extract involves (a) removing e.g. head of skipjack tuna and mincing, adding 80-100 degrees C water to the minced skipjack tuna, stirring and boiling to obtain skipjack slurry, (b) hydrolyzing skipjack slurry with protease, inactivating protease enzyme and centrifuging to obtain supernatant containing crude enzymolyzed solution, (c) adding activated carbon to the crude enzymolyzed solution, stirring and filtering with filter paper to obtain purified enzymolyzed solution and (d) concentrating and spray drying purified enzymolyzed solution.    USE - The method is useful for preparing skipjack tuna extract which is used as healthcare product or food in the form of capsule, tablet, pill, powder or granule for providing uric acid lowering effect (claimed) and treating hyperuricemia.    ADVANTAGE - The method of preparing skipjack tuna extract is simple, cost-effective and environmentally-friendly and has no toxic side effects.    DETAILED DESCRIPTION - Method of preparing skipjack tuna extract involves (a) removing head, internal organs and impurities of skipjack tuna, mincing the skipjack tuna and adding 1-2 times 80-100 degrees C water, stirring and boiling skipjack tuna for 20-30 minutes to obtain skipjack slurry, (b) adding 1.6-3.2 wt.% protease to the skipjack slurry and hydrolyzing for 6-9 hours at 50-55 degrees C, inactivating the added protease enzyme at 85-95 degrees C for 15-30 minutes and centrifuging the hydrolyzed slurry to obtain supernatant containing crude enzymolyzed solution, (c) adding 0.5-1 wt.% activated carbon to the crude enzymolyzed solution and stirring the mixture at 45-55 degrees C for 0.5-1 hour and filtering the mixture using 0.5 mu m filter paper to obtain purified enzymolyzed solution and (d) concentrating the purified enzymolyzed solution under vacuum and spray drying to obtain skipjack tuna extract. An INDEPENDENT CLAIM is included for use of the skipjack tuna extract prepared by the above method in healthcare product or food.