TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preparation (claimed): 2,3-Amino-7-halo-9,9'-dialkylfluorene of formula (II) and 9H-fluorene-2,3-diamine of formula (III) are subjected to amidation reaction, to obtain intermediate 7-halo-dialkyl-substituted fluorenyl-10,10'-2-aryl-imidazole. The intermediate is reacted with aryl boronic acid of formula: Ar'-B(-OH)2 (IV) and alkali in molar ratio of 1:1.2-2:1-2.5 in solvent, in presence of palladium catalyst under inert atmosphere protection at 60-90 degrees C, mixture is cooled to room temperature, extracted with ethyl acetate, and organic phase is spin-dried, separated and purified to obtain asymmetric fluorene-imidazole derivative (I).R4=chloro, bromine or iodo;X=aldehyde, carboxy, acid chloride group, carboxylate or carboxylic acid group;andAr'=benzyl, naphthalenyl, anthracenyl, phenanthrenyl, pyrenyl, fluorenyl, pyrazinyl, pyrrolyl, pyrazolyl, oxazolyl, thiazolyl, thiophenyl, carbazolyl, pyridinyl, piperidinyl, purinyl, quinolinyl, isoquinolinyl, morpholinyl, quinazolinyl, biphenyl, benzo-anthracenyl, triphenylenyl, diphenylamino, triphenylamino, benzofuranyl, benzoxazolyl, benzisoxazolyl, monosubstituted benzyl chosen from chloro-substituted benzyl, fluoro-substituted benzyl, nitrobenzyl, trifluoromethylbenzyl, methylbenzyl, ethylbenzyl, cumenyl, tert-butylbenzyl or methoxybenzyl or polysubstituted benzyl chosen from o-xylene, m-xylene, o-difluorobenzyl, m-difluorobenzyl, o-dimethoxybenzyl, m-dimethoxybenzyl or N,N-dimethylbenzyl.Preferred Process: The method further involves using pH-adjusting agent. Preferred Components: The palladium catalyst is palladium chloride, palladium acetate, tetrakis(triphenylphosphine)palladium(0), bis(triphenylphosphine)palladium(II) dichloride or (1,1'-bis(diphenylphosphino)ferrocene)dichloropalladium(II). The organic solvent is chosen from dioxane/water, toluene/water, toluene/methanol, toluene/ethanol, toluene/tetrahydrofuran, toluene/ethanol/water, acetonitrile/water, N,N-dimethylformamide/water, tetrahydrofuran and dimethylsulfoxide. The pH-adjusting agent is chosen from potassium carbonate, potassium phosphate, potassium fluoride, sodium carbonate, sodium hydrogen carbonate, sodium hydroxide, sodium ethoxide, tert-butyl sodium alkoxide, cesium fluoride, cesium carbonate, lithium carbonate and barium hydroxide. Preferred Definitions:    aryl or heteroaryl=groups chosen from 38 groups e.g. benzo-anthracenyl, triphenylenyl, indazolyl, benzoxazolyl, isoxazolyl, benzisoxazolyl, quinoxalinyl, acridinyl, quinazolinyl, pyridazinyl or cinnolinyl.