NOVELTY - Theophylline synthesis involves heating sodium acetate trihydrate, 6-amino-1,3-dimethyl uracil, and acetic anhydride in a reaction vessel at 124-127 degrees C for 28-31minutes, and then cooling at room temperature with stirring for 47-50 hours. The cooled reaction mixture is filtered with a concentration of 98 wt.% to form a filter cake, which is washed with acetic acid, and then dried to give 6-amino-5-bromo-1,3-dimethyl-uracil. The obtained 6-amino-5-bromo-1,3-dimethyl uracil and benzylamine are heated in another reaction vessel at 98-100 degrees C for 1.9-2.2 hours with stirring constantly.    USE - Method for synthesizing theophylline (claimed).    ADVANTAGE - The method synthesizes the theophylline in a simple, safe, cost-effective and eco-friendly manner with high yield and high purity.    DETAILED DESCRIPTION - Theophylline synthesis involves heating sodium acetate trihydrate, 6-amino-1,3-dimethyl uracil, and acetic anhydride in a reaction vessel at 124-127 degrees C for 28-31minutes, and then cooling at room temperature with stirring for 47-50 hours. The cooled reaction mixture is filtered with a concentration of 98 wt.% to form a filter cake, which is washed with acetic acid, and then dried to give 6-amino-5-bromo-1,3-dimethyl-uracil. The obtained 6-amino-5-bromo-1,3-dimethyl uracil and benzylamine are heated in another reaction vessel at 98-100 degrees C for 1.9-2.2 hours with stirring constantly, and then cooled at room temperature in an ice water to form precipitate. The formed precipitate is washed with ice-water, and then dried to give 6-amino-5-benzyl-1,3-dimethyl uracil. The obtained6-amino-5-benzyl-1,3-dimethyl uracil, p-toluenesulfonic, triethylorthoformate and dimethyl fumarate are heated in a third reaction vessel at 68-71 degrees C for 46-49 hours, and then cooled at room temperature to form solid precipitate. The formed precipitate is washed with water and acetone, and then dried to give 1,3-dimethyl-7-benzyl-xanthine. The obtained 1,3-dimethyl-7-benzyl-xanthine and hydrogen are in an autoclave with palladium on charcoal catalyst and methanol to form a mixture. The formed mixture is filtered through celite, where the filtrate is purified in rotary evaporator by silica gel column chromatography to give the theophylline.