NOVELTY - Mushroom cultivation substrate comprises 10-20 wt.% hemp shell, 10-20 wt.% lotus seed shell, 10-20 wt.% walnut shell, 10-20 wt.% almond shell, 20-50 wt.% sawdust, 10-15 wt.% wheat bran, 4-6 wt.% Sorghum flour, 4-6 wt.% wheat flour, 1-2 wt.% bean cake, 2-3 wt.% peanut bran, 1-2 wt.% fructus cannabis bran, 1-2 wt.% beef powder, 2-3 wt.% lime powder, and 1-2 wt.% sugar.    USE - Used as mushroom cultivation substrate.    ADVANTAGE - The substrate provides high protein and amino acid total quantity than ordinary mushroom. The mushroom cultivated has good taste, flavor, and excellent quality. The cultivation method provides high yield per unit area of mushroom shed.    DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for cultivating mushroom using mushroom cultivation substrate comprising (i) mixing and fermenting: providing hemp shell, lotus seed shell, walnut shell, almond shell powder, crushing, adding water, stirring, adding in fermentation reactor and fermenting for 1-3 days, each turning every day, providing sawdust, wheat bran, Sorghum flour, wheat flour, bean cake, peanut bran, soybean bran, fructus cannabis bran, beef powder, lime powder, adding candy water, mixing uniformly, fermenting for 1-2 days, (ii) packaging, sterilizing and inoculating, (iii) carrying out hyphae management: culturing mushroom in the culture chamber in a dark environment, where the indoor temperature is controlled at 25-26 degrees C, ventilating air exchange, keeping air fresh, maintaining humidity not exceeding 70%, (iv) carrying out mushroom management: mixing nutrient slurry and water to preparing concrete column in the mushroom shed, surrounding the column with mushroom adhesive nutrient soil, each column is filled with nutrient mud, when hyphae grows in the column, removing mushroom from column and placing in bag, inserting dropping water pipe in part of the mud column, then processing primordium, where the inducement process temperature and humidity is as follow: (a) controlling temperature, covering insulating film, film cooling open, continuously stimulating for 5-7 days, (b) controlling temperature, separating 2-3 days not spraying water to fungus stick, then following days spraying every 3-4 times, continuously for 3-5 days, after mushroom bud shows up, heating preserving and moisturizing, temperature controlling mushroom shed at 12-22 degrees C, controlling humidity at 80-95%, maintaining the moisture for 5-7 days, and (v) harvesting.