NOVELTY - Enhancement method of blueberry anthocyanin oxidation resistance includes mixing anhydrous phenolic acid, acetic anhydride and pyridine, stirring under nitrogen atmosphere, mixing with anhydrous thionyl chloride, stirring, recrystallizing with aprotic solvent, adding acetone, placing into ice bath, dropping sodium hydroxide while stirring, and adjusting pH to obtain phenolic acid reagent; and adding blueberry anthocyanin, adding into dioxane, gradually dropping triethylamine, stirring, reacting, evaporating dioxane and triethylamine, adding hydrochloric acid, filtering, washing, and drying.    USE - Method for enhancement of blueberry anthocyanin oxidation resistance used for food, healthcare products, cosmetics and medicine (claimed).    ADVANTAGE - The method enhances oxidation resistance and improves stability of blueberry anthocyanin, and it has higher degree of acylation of up to 53-70%, short entire process, easy to control parameters, easy to obtain raw materials, mild reaction condition, lower production costs, and no pollutant emissions.    DETAILED DESCRIPTION - Enhancement method of blueberry anthocyanin oxidation resistance comprises:    (A) mixing anhydrous phenolic acid, acetic anhydride and pyridine at molar ratio of 1:1-6:1-6, stirring at 50-70 revolutions/minute at room temperature for 20-30 minutes under nitrogen atmosphere to obtain acetylated phenolic acid; mixing with anhydrous thionyl chloride at molar ratio of 1:1-5, stirring to 30-100 degrees C at speed of 80-100 revolutions/minute for 1-24 hours, and recrystallizing with aprotic solvent to obtain acetylated phenolic acid chloride; and adding 1-1.5 times acetone, mixing, placing into ice bath, dropping sodium hydroxide while stirring at 50-80 revolutions/minute for 3-5 hours, and adjusting pH to 7-9 to obtain phenolic acid reagent; and    (B) adding blueberry anthocyanin at ratio of 1:3-10, adding into dioxane under nitrogen atmosphere, gradually dropping 3-10 mol triethylamine, stirring at 70-80 revolutions/minute, reacting to 30-60 degrees C for 2-12 hours, evaporating dioxane and triethylamine under reduced pressure, adding hydrochloric acid to adjust pH to 1-4, filtering, washing, and vacuum-drying.