TECHNOLOGY FOCUS - ORGANIC CHEMISTRY - Preparation (Claimed): The preparation of (I) comprises: either performing Buchwald coupling of fluorene derivatives with a leaving group containing substituted amine compounds of formula (Ar1-NH-Ar1) (III) in a single step process; or performing Buchwald coupling of fluorene derivatives with a leaving group containing substituted amine compounds of formulae (Ar2-NH2) (IVa) and (Ar1-NH2) (IVb) in a two step process to obtain (I). Preferred Method: The method comprises (a) addition of an organometallic compound benzochromene-6-one, (b) performing acid catalyzed cyclization reaction to obtain 4-hydroxy-fluorene derivative, (c) conversion of the hydroxy group in position 4th of fluorene to a leaving group and (d) converting the fluorene to obtain (I). Preferred Components: (I) is prepared from compound of a benzochromene-6-one. Preferred Definitions:    B1=phenylene, biphenylene, terphenylene, naphthylene, pyridinylene, pyrimidinylene, pyrazinylene, pyridazinylene, triazinylene, fluorenylne, dibenzofuranylene or dibenzothiophenylene (all optionally substituted with R4).    ACTIVITY - Antipsoriatic; Dermatological; Hepatotropic; Antiinflammatory; Vulnerary; Antiseborrheic. No biological data given.    MECHANISM OF ACTION - None given.    SPECIFIC COMPOUNDS - 70 Compounds (I) are disclosed, e.g. biphenyl-4-yl-(9,9-dimethyl-9H-fluoren-2-yl)-(4-(9-methyl-9-phenyl-9H-fluoren-4-yl)-phenyl)-amine of formula (Ia), bis-(9,9-dimethyl-9H-fluoren-2-yl)-(4-(9,9-diphenyl-9H-fluoren-4-yl)-phenyl)-amine, bis-(9,9-dimethyl-9H-fluoren-2-yl)-(4-(9,9-diphenyl-9H-fluoren-4-yl)-phenyl)-amine, biphenyl-3-yl-(9,9-dimethyl-9H-fluoren-2-yl)-(4-(9,9-diphenyl-9H-fluoren-4-yl)-2,5-dimethyl-phenyl)-amine and (4-dibenzofuran-4-yl-phenyl)-(9,9-dimethyl-9H-fluoren-2-yl)-(4-(9,9-diphenyl-9H-fluoren-4-yl)-phenyl)-amine.    EXAMPLE - 20 g 4,4,5,5-Tetramethyl-2-(9-methyl-9-phenyl-9H-fluoren-4-yl)-(1,3,2)dioxaborolane, 20.8 g biphenyl-4-yl-(4-chloro-phenyl)-(9,9-dimethyl-9H-fluoren-2-yl)-amine and 13.4 g cesium fluoride were suspended in 265 ml dioxane, then 3.9 g bis(tricyclohexylphosphine)palladium(II)dichloride) was added and heated and refluxed for 18 hours to obtain reaction solution. Then the solution reaction was cooled, an organic phase was separated and filtered through silica gel, washed three times with 100 ml water and then concentrated to dryness, crude product was passed through silica gel using toluene, and residue was recrystallized from heptane/toluene, and sublimed in high vacuum to obtain 26.5 g biphenyl-4-yl-(9,9-dimethyl-9H-fluoren-2-yl)-(4-(9-methyl-9-phenyl-9H-fluoren-4-yl)-phenyl)-amine with 80% yield.