NOVELTY - Extracting magnolol and honokiol from Magnolia officinalis leaves involves crushing dry leaves of Magnolia officinalis; extracting the leaves powder with methanol or ethanol alkaline solution to obtain extract; dissolving the extract with 9-10 times water, extracting with using methylene chloride for 2-3 times to obtain sample liquid; taking small hole diameter of separating resin pressurizing column, filling acetone water solution in column, collecting the magnolol and honokiol liquid, concentrating, and purifying to obtain magnolol and honokiol.    USE - For extracting magnolol and honokiol from Magnolia officinalis leaves useful for preparation of drug for treating bacterial infection, inflammatory disease, anxiety, depression, cancer, aging, myocardial disease and hypoglycemia (claimed).    ADVANTAGE - The method provides extract that has more than 98% magnolol and honokiol content and high purity; and is simple and safe, has short production period, is low cost, and reduces environment pollution.    DETAILED DESCRIPTION - Extracting magnolol and honokiol from Magnolia officinalis leaves involves crushing dry leaves of Magnolia officinalis; extracting the leaves powder with methanol or ethanol alkaline solution having pH of 9-10 at 60-70 degrees C for 2-3 times, where each time for 0.5-3h, combining the extraction liquid, regulate the pH value to 6-7 by using acid, recovering solvent to obtain extract; dissolving the extract with 9-10 times water, extracting with using methylene chloride for 2-3 times, or using aluminum oxide absorbing, collecting effluent liquid, evaporating to dryness to obtain sample liquid; taking small hole diameter of separating resin pressurizing column, filling 35-50 vol.% methanol or ethanol or acetone water solution in column, then the upper dripping a sample liquid slowly, sampling after standing in turn with 1-1.5 hours, collecting the magnolol and honokiol liquid, concentrating, and purifying to obtain magnolol and honokiol.