NOVELTY - Extraction of galantamine from Lycoris involves adding water to processed Lycoris powder, adjusting pH to 4.5, adding hybrid enzyme containing cellulase and pectinase, hydrolyzing, ultrasonically-treating, centrifuging to obtain supernatant containing galantamine extract, washing supernatant with sodium hydroxide, extracting using trichloromethanesulfonic acid, subjecting concentrate to cation exchange process, 18C-reverse phase silica gel column chromatography and normal-phase silica gel chromatography, recrystallizing and vacuum-drying.    USE - Extraction of galantamine from Lycoris (claimed).    ADVANTAGE - The method is environmentally-friendly, and enables efficient and economical extraction of galantamine from Lycoris with high extraction rate, reduced usage amount of solvent, and high purity of 99.2%, by simple method.    DETAILED DESCRIPTION - Extraction of galantamine from Lycoris involves adding water to the processed Lycoris powder, adjusting pH to 4.5, adding 1-3% hybrid enzyme containing cellulase and pectinase in ratio of 1:1, hydrolyzing at 50 degrees C for 20-100 minutes, ultrasonically-treating for 5-25 minutes, centrifuging at rate of 5000 rpm for 20 minutes to obtain supernatant containing galantamine extract, washing supernatant containing galantamine extract with sodium hydroxide such that pH is adjusted to 10, extracting using trichloromethanesulfonic acid, leaving still overnight, adjusting pH at 2 using hydrochloric acid, filtering to obtain galantamine concentrate, subjecting the concentrate to cation exchange process using D-001-type cation exchange resin, drying the product, performing 18C-reverse phase silica gel column chromatography using methanol-water, concentrating, vacuum freeze-drying, performing normal-phase silica gel chromatography of the dried product using eluent chosen from petroleum ether, ethyl acetate, chloroform, acetone and methanol, evaporating solvent, concentrating, vacuum freeze-drying, recrystallizing the dried product using ethanol, and vacuum-drying at 50-60 degrees C.