NOVELTY - Method for removing acetaminophen involves supplying water into vertical flow reactor bioretention system including a pretreatment layer, biopurification layer and depth processing layer, filtering to remove precipitate and nutrient solution, adding dissolved oxygen, soaking the pretreatment layer in the reaction liquid, filtering water to remove precipitate and nutrient solution, adding dissolved oxygen, soaking the biopurification layer and depth processing layers in the reaction liquid, adding enriched broth, culturing microorganisms, and treating water in two stages.    USE - Removal of acetaminophen from urban sewage, agricultural waste.    ADVANTAGE - The method enables efficient removal of acetaminophen from sewage water by simple method.    DETAILED DESCRIPTION - Method for removing acetaminophen involves using vertical flow reactor bioretention system including a pretreatment layer, biopurification layer and depth processing layer, filtering water using filters to remove precipitate and nutrient solution, adjusting pH to 6-7, adding 2-3 mg/L dissolved oxygen, soaking the pretreatment layer in the reaction liquid in reactor, filtering water using filters to remove precipitate and nutrient solution, adjusting pH to 6-7, adding 2-3 mg/L dissolved oxygen, soaking the biopurification layer and depth processing layers in the reaction liquid in reactor at 20-30 degrees C, adding enriched broth to reactor, culturing microorganisms to remove acetaminophen, placing pretreatment layer in the reactor inlet side, and treating water in two stages. Stage (i) includes suspended solid content of less than 100 mg/L, chemical oxygen demand concentration of less than 50 mg/L, and acetaminophen concentration of less than 5 mg/L, dissolved oxygen concentration in the secondary effluent of 1-2 mg/L and effluent detect acetaminophen removal of more than 50%, and stage (ii) includes suspended solid concentration of less than 100 mg/L, ammonia content of less than 50 mg/L, chemical oxygen demand of 200 mg/L, acetaminophen concentration of less than 10 mg/L, and dissolved oxygen concentration in the secondary effluent of 0.2-0.5 mg/L. The pretreatment layer is sand filling layer. The biopurification layer includes layers of volcanic rocks. The nutrient solution contains carbon and nitrogen in ratio of 2-3:1. The carbon source is acetic acid and/or sodium bicarbonate.