NOVELTY - Decontaminating-1 equipment used in at least one of a fermentation or distillation process, comprises: separating at least one of an off-specification product or lights purge material from a stream of distillation product capable of being subject to contamination from at least one of a distillation process or a fermentation process associated with distillation process or separating at least one process solvent stream from a distillation process or a fermentation process; and cleaning equipment with a solution comprising the at least one of off-specification products or lights purge material.    USE - The method is useful for decontaminating equipment used in at least one of a fermentation or distillation process for biofuel production.    ADVANTAGE - The method provides decontamination of equipment, where the contamination comprises a microorganism that produces a co-product and the method maintains production of a minor co-product at or below the ratio (claimed).    DETAILED DESCRIPTION - Decontaminating-1 equipment used in at least one of a fermentation or distillation process, comprises: separating at least one of an off-specification product or lights purge material from a stream of distillation product capable of being subject to contamination from at least one of a distillation process or a fermentation process associated with the distillation process or separating at least one process solvent stream from a distillation process or a fermentation process; and cleaning the equipment with a solution comprising the at least one of off-specification products or lights purge material or the process solvent stream to minimize contamination associated with the distillation product. INDEPENDENT CLAIMS are also included for:    (1) method-2 for decontaminating equipment used to produce butanol, comprising generating a solution for cleaning equipment used to produce butanol from at least one of butanol that does not meet a product specification or a lights purge material that results from distillation of butanol produced by a fermentation, the solution comprising butanol or lights purge material at sufficiently high concentration to minimize or eliminate contamination, but is insufficient to appreciably inhibit a recombinant microorganism used in the fermentation and cleaning at least a portion of the equipment with the solution to minimize contamination that results from production of the butanol;    (2) a fermentation system for producing butanol, comprising at least one vessel configured to ferment butanol and a cleaning system configured to provide a solution that comprises at least one of an off specification product or lights purge material obtained from a distillation system associated with the fermentation system or a process solvent stream from the fermentation system or the distillation system for cleaning at least a portion of the fermentation system or the distillation system;    (3) a cleaning system configured for use with a facility for continuously producing product alcohol, comprising a vessel configured to be placed in fluid connection with a purge stream to remove material that is not to be included in product alcohol the vessel is additionally configured to be placed in fluid connection with equipment included in the facility and operable to clean the equipment to minimize contamination with the material at a predetermined temperature;    (4) at least partially decontaminating-3 a fermentation system configured to perform continuous fermentation;    (5) decontaminating-4 an ISPR system for a fermentation process;    (6) decontaminating-5 ISPR system included in a fermentation system that is configured to produce fermentation product;    (7) decontaminating-6 an ISPR system for a fermentation process;    (8) a fermentation system-7 for generating fermentation product;    (9) reducing-8 contamination in fermentation feedstock;    (10) decontaminating-9 a static mixer in an ISPR system;    (11) minimizing-10 contamination in conversion of maize oil to maize oil fatty acid (COFA);    (12) decontaminating-11 a fermentation system that implements extractant to recover product from a fermentation broth;    (13) recovering-12 an extractant from a fermentation system that implements extractant to recover product alcohol from a fermentation broth, comprising; and    (14) decontaminating-13 fermentation system that implements an extractant to recover a product from fermentation broth.